Metachromatic LeukodystrophyNext Topic
Metachromatic leukodystrophy, or MLD, is an inherited disorder that causes fatty substances, also called
lipids, to accumulate in key cells throughout the body. MLD affects the nerves running through the hands, feet, and other
parts of the body (known as the peripheral nervous system, or PNS) and also affects the brain and spinal cord (known as the
central nervous system, or CNS). The symptoms of MLD occur at varying ages and sometimes progress rapidly to a
life-threatening stage within a few years of diagnosis. In other cases, MLD symptoms develop over a period of 10 or more
years following diagnosis.
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